Protein Alignment CkIalpha and Csnk1e

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001398810.1
• Gene: Csnk1e / 27373
• MGIID: 1351660
• Length: 431
• Species: Mus musculus
• Alignment Length: 330
• Identity: 214/330 - (64%)
• Similarity: 257/330 - (77%)
• Gaps: 14/330 - (4%)

  Fly    13 EIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFP 77
            |:.||.|||:.||||||||||||||.:|.||||||||:|....:||||..|:|.|:::.||||.|
Mouse     2 ELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQGGVGIP 66

  Fly    78 RIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKP 142
            .|:..|.|.::|.:||:|||||||||||||:|.|::||||:|.||||.|:||||.|.|||||:||
Mouse    67 SIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKP 131

  Fly   143 DNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDM 207
            ||||||:|:..|.:::||||||||:||..|..||.|||:|||||||||||||.|||||||||||:
Mouse   132 DNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDL 196

  Fly   208 ESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRSLRFE 272
            ||||||:||||.|.|||||:||.||:||||:||||||||||||||||.|:|||.|||:||||||:
Mouse   197 ESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFSTYLNFCRSLRFD 261

  Fly   273 EQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLK---QKTHQ------GQPNPAILLEQLDKDKEK 328
            ::|||.|||||||.||......|||::||.|||   ...||      |:|.     :||....|.
Mouse   262 DKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFMRPPFHQPPALPCGRPQ-----DQLGCSPES 321

  Fly   329 QNGKP 333
            :..:|
Mouse   322 RGCRP 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	190/264 (72%)
Csnk1e	NP_001398810.1	STKc_CK1_delta_epsilon	8..282	CDD:271027	195/273 (71%)