Protein Alignment CkIalpha and ZK666.8

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_496261.2
• Gene: ZK666.8 / 191385
• WormBaseID: WBGene00014048
• Length: 391
• Species: Caenorhabditis elegans
• Alignment Length: 233
• Identity: 81/233 - (34%)
• Similarity: 116/233 - (49%)
• Gaps: 20/233 - (8%)

  Fly    10 SRPEIIVGGKYR----VIRKIGSGSFGDIYLGMSIQSGEEVAIKME----SAHARHPQLLYEAKL 66
            |.|.:.:..|:|    :...||.|.:|:|||.:.::..||||||.|    ........:|.:|.|
 Worm    79 STPLMPIDEKFRKRWHIEGIIGKGGYGEIYLAIDMKLAEEVAIKAEPLVRKGKIARRMILEQAVL 143

  Fly    67 YRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFC-TRHFTIKTVLMLVDQMIGRLEYI 130
            .: |.|....|.|...|..:|||.:|:.||..:|.|:.... ||..:..:|..:..|.|..|..:
 Worm   144 VK-LQGKPHVPWIFGSGHTENFNFIVLQLLSANLGDIRRMSPTRKLSKSSVGRIAVQAIAALRDL 207

  Fly   131 HLKCFIHRDIKPDNFLMGI---GRHCNKLFLIDFGLAKKFRDP--HTRHHIVYREDKNLTGTARY 190
            |...::||||||.|...||   .||.  |.|:||||.::::||  ..|.|   |......||.||
 Worm   208 HDVGYLHRDIKPGNMCFGITSKTRHV--LMLLDFGLVRRYKDPDGEWRTH---RVKAGFRGTQRY 267

  Fly   191 ASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMK 228
            .|...|..:||:..|||.||.|.::....|.|||:.::
 Worm   268 VSTRVHRRLEQTPTDDMVSLLYTLIELLAGELPWRNIE 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	79/224 (35%)
ZK666.8	NP_496261.2	Protein Kinases, catalytic domain	92..354	CDD:473864	77/220 (35%)