Protein Alignment CkIalpha and T15B12.2

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001367879.1
• Gene: T15B12.2 / 188528
• WormBaseID: WBGene00020531
• Length: 446
• Species: Caenorhabditis elegans
• Alignment Length: 330
• Identity: 93/330 - (28%)
• Similarity: 154/330 - (46%)
• Gaps: 32/330 - (9%)

  Fly    26 IGSGSFGDIYLGMSIQSGE-EVAIKMESAHARHPQLLYEAKLYR-ILSGGVGFPRIRH------H 82
            ||||.|||:|......:.: |.|:|.|...|:..:|..|..:.: |.:......:.||      .
 Worm    57 IGSGGFGDVYRVYDEPNPKMEYAMKTEVHGAQQRRLSIEKSILKEIDTYTTTHKKSRHFCELIDS 121

  Fly    83 GKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLM 147
            |:.|:::.:||.|:|||||.:.....|.:|...|:.:..|::..:|.:|...|||||:||.|...
 Worm   122 GQTKDYSWIVMTLIGPSLESVRRMLKRQYTKSCVINMALQILDAVEVMHEVGFIHRDLKPANICT 186

  Fly   148 GI-GRHCNKLFLIDFGLAKK-FRDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSRRDDMESL 210
            |. .:..:.|:::|||:::: |:..........||.....||.:::|...|...:|.|:||||:.
 Worm   187 GTPPQDDHVLYVLDFGISRRVFKSSKCHELRNKRERVPFFGTRKFSSRACHQEKDQGRKDDMETY 251

  Fly   211 GYVM--MYFNRGVLPWQGMKANTKQQKYEKISEKK---MSTPIEVLCKGSPAEFSMYLNYCRSLR 270
            .|.:  ::.|...|.|....|:.     .||.|||   ...|.:.|.|..|:.....:.|.|.|:
 Worm   252 LYTILDLFHNERGLSWSKDLADV-----NKIIEKKHALFENPTKELDKIIPSGIDNIIVYLRGLK 311

  Fly   271 FEEQPDYMYLRQLFRILFRTL--NHQYDYIYDWT-MLKQKTHQGQPNPAI---------LLEQLD 323
            ||:..||..:....|...:.:  :...|...||| .|:|...:...|.|:         |.|:|.
 Worm   312 FEDPVDYRQIENELRTAGKKMAPSDSSDETMDWTGKLEQLLKEANKNKAVGTPKGEETLLYERLK 376

  Fly   324 KDKEK 328
            ..:::
 Worm   377 AKRDR 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	81/272 (30%)
T15B12.2	NP_001367879.1	STKc_TTBK	51..353	CDD:270919	88/300 (29%)