DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CkIalpha and K09C6.2

DIOPT Version :9

Sequence 1:	NP_001162737.1	Gene:	CkIalpha / 32221	FlyBaseID:	FBgn0015024	Length:	337	Species:	Drosophila melanogaster
Sequence 2:	NP_503344.2	Gene:	K09C6.2 / 187199	WormBaseID:	WBGene00019556	Length:	634	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	58/281 - (20%)
Similarity:	103/281 - (36%)	Gaps:	63/281 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PEIIVGGKYRVIRKI--------GSGSFGDIYLGMSIQSGEEVAIKMES-AHARHPQLLYEAKLY 67
            |..:...||.::.::        .|.:....:|..||:||...:.|:.| .:..|.||..:....
Worm     2 PRFLKKTKYEMMEELDPDGPPESSSSTSNQFWLVQSIRSGCMRSAKLASQKNPEHLQLQKDLNKQ 66

  Fly    68 R--------ILSGGVGFPRIRHHGKEKNFNTLV-----MDLL------GPSLEDLFNFCTRHFTI 113
            |        .||......|:...|.:.:|..|:     ||.|      ||.|.....|...:||.
Worm    67 RKLLFDLLPELSNPSHIARLVDVGYDDDFKFLIFEDFGMDFLTLFDEFGPVLNPATLFLISYFTF 131

  Fly   114 KTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHIVY 178
            ..:           :.:|....:|.||:|.:|  .:.:|...:.:.|:....      ||
Worm   132 NAI-----------KELHSFDIVHLDIRPSSF--SVNQHPFNIKITDYSRCM------TR----- 172

  Fly   179 REDKNLTGTARYASINAHLGIEQSRR----DDMESLGYVMMYF-NRGVLPWQGMKANTKQQKYEK 238
            :.:..:...||..|.:..:..::..:    .|.|:..|.|::. ....|||.|...|..     :
Worm   173 KPEMKVPDDARPDSFSPRVFHQKDAQFDEFVDFEAWVYTMLFLCTVEKLPWFGDAENML-----R 232

  Fly   239 ISEKKMSTPIEVLCKGSPAEF 259
            :.|:..:.|:..|..|. |:|
Worm   233 LKEEFFNDPLNYLYDGC-ADF 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	57/274 (21%)
CkIalpha	NP_001162737.1	Pkinase_Tyr	23..284	CDD:285015	55/270 (20%)
K09C6.2	NP_503344.2	SPS1	72..>224	CDD:223589	34/175 (19%)
K09C6.2	NP_503344.2	PTZ00121	<270..>455	CDD:173412
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900