Protein Alignment CkIalpha and kin-20

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_001024669.1
• Gene: kin-20 / 181620
• WormBaseID: WBGene00002203
• Length: 497
• Species: Caenorhabditis elegans
• Alignment Length: 299
• Identity: 193/299 - (64%)
• Similarity: 241/299 - (80%)
• Gaps: 3/299 - (1%)

  Fly     8 KESRPEIIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSG 72
            |::..|:.||.::|:.||||||||||||||.:||:.||||:|:|...::||||..|::||||:.|
 Worm   179 KKAEMELRVGNRFRLGRKIGSGSFGDIYLGQNIQTNEEVAVKLECVKSKHPQLHIESRLYRIMLG 243

  Fly    73 GVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIH 137
            |:|.|.||..|:|.::|.:||:|||||||||||||.|.|::||||:|.|||:.|:|:||.:.:||
 Worm   244 GIGIPEIRWCGQEGDYNVMVMELLGPSLEDLFNFCQRKFSLKTVLLLADQMLSRVEFIHCRDYIH 308

  Fly   138 RDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRH-HIVYREDKNLTGTARYASINAHLGIEQ 201
            |||||||||||:|:..|.:::|||||||::||  ::| ||.|||:|||||||||||||.|.||||
 Worm   309 RDIKPDNFLMGLGKRGNLVYIIDFGLAKRYRD--SKHQHIAYRENKNLTGTARYASINTHRGIEQ 371

  Fly   202 SRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYC 266
            |||||:||||||.||||||.|||||:||.||:||||.|||||:||.::.||.|.|..|:.|||||
 Worm   372 SRRDDIESLGYVFMYFNRGTLPWQGLKAVTKRQKYELISEKKISTRVDDLCAGYPEAFAQYLNYC 436

  Fly   267 RSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLK 305
            |||.|||||||.|||.|||.||......|||::||...|
 Worm   437 RSLGFEEQPDYGYLRNLFRTLFHRQQFCYDYVFDWNTYK 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	178/265 (67%)
kin-20	NP_001024669.1	STKc_CK1_delta_epsilon	190..463	CDD:271027	183/274 (67%)