Protein Alignment CkIalpha and C50F4.10

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_505456.2
• Gene: C50F4.10 / 179334
• WormBaseID: WBGene00008235
• Length: 317
• Species: Caenorhabditis elegans
• Alignment Length: 321
• Identity: 94/321 - (29%)
• Similarity: 152/321 - (47%)
• Gaps: 51/321 - (15%)

  Fly    19 KYRVIRKIGSGSFGDIYL--GMSIQSG-EEVAIKMESAHARHPQLLYEAKLYRILS--GGVGFPR 78
            |:.:.:||..|.|..||:  |.|..|. ::.|:|.|||.:....|..||.:.:.::  |...|..
 Worm    18 KWTIEKKIAQGDFNFIYMCNGSSNMSNYKQFALKCESAQSPLQMLKVEAFVLQTIAKRGSRHFCD 82

  Fly    79 IRHHGKEKNFNTLVMDLLGPSLED-LFNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKP 142
            |...||.:..:.:||.::|.:|.| :....:...::...|.:..|:|..||.:|...|||||:||
 Worm    83 IEDIGKFQGIHYIVMHMIGRALVDYMKTSMSGAISVNCALSVGIQLIEALEDLHNCGFIHRDLKP 147

  Fly   143 DNFLMG------IGRHCNKLFLIDFGLAKKFRDPHT-----RHHIVYREDKNLTGTARYASINAH 196
            .|...|      :|    ||:|:.||:::::.|...     |.::.:|      ||.||||:|.|
 Worm   148 SNICFGRKDRNELG----KLYLLSFGISRRYLDSKNQMRKPRDNVEFR------GTVRYASLNCH 202

  Fly   197 LGIEQSRRDDMESLGYVMMYFNRGVLPWQGMK-----ANTKQQKYEKISEK---KMSTPIEVLCK 253
            ...|.:|:||:||..||::....|.|||:|:.     |..|||.....:..   :...|:|.|
 Worm   203 QLQELNRKDDLESAFYVIVEMITGQLPWKGLPDGAAVARVKQQSRHPSAIALFLRAPCPMEEL-- 265

  Fly   254 GSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQPN 314
               .|..:.::   |..:...|||:.:..:.|...|. :.|.::.|||       .||..|
 Worm   266 ---REVMILID---SYNYFTAPDYVNICNILRRAMRR-SPQPEHPYDW-------EQGGTN 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	85/289 (29%)
C50F4.10	NP_505456.2	Protein Kinases, catalytic domain	18..291	CDD:473864	85/290 (29%)