Protein Alignment CkIalpha and C27D8.1

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_502428.1
• Gene: C27D8.1 / 178226
• WormBaseID: WBGene00007777
• Length: 327
• Species: Caenorhabditis elegans
• Alignment Length: 319
• Identity: 87/319 - (27%)
• Similarity: 149/319 - (46%)
• Gaps: 46/319 - (14%)

  Fly    20 YRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMES--AHARHPQLLYEAKLYRILSGGVGFPRIRHH 82
            |.|:|.:|.|.||.:||....:|.::.|:|:|.  ...:|.:|..|..:.:::..|..|.:|...
 Worm    24 YTVVRLLGEGGFGAVYLVQDNKSKKQSAMKVERKIEKRKHSKLKMEIAILKLVGSGKHFTQIVDR 88

  Fly    83 GK--EKNFNTLVMDLLGPSLEDL--------FNFCTRHFTIKTVLMLVDQMIGRLEYIHLKCFIH 137
            ||  ::.|..|||:|:|.||.||        |:|.|.       |.:..|.:..:|.:|...|||
 Worm    89 GKKDKEGFFFLVMELVGKSLADLKADRPDKVFSFATG-------LGVSCQCLEAVEELHKTGFIH 146

  Fly   138 RDIKPDNFLMGIGRHCNKLFLIDFGLAKKFRDPHTRHHI-VYREDKNLTGTARYASINAHLGIEQ 201
            ||:||.|:..|:....:.::::|||:|:|:.  :|::.: ..||.....||.|:|.|..|...|.
 Worm   147 RDLKPQNYACGLDEKRHNIYILDFGIARKYL--NTKNELKTPRETVGFKGTVRFAPIACHRNTEM 209

  Fly   202 SRRDDMESLGYVMM-YFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAE------- 258
            ..:||.||..|::: ......|||:.:     ..|:|.:.||:.       |:.....
 Worm   210 GPKDDCESWFYLLLDLIVPSGLPWRKL-----SDKHEVLKEKEE-------CRKDKRSSLFAGLR 262

  Fly   259 ----FSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTHQGQP 313
                .|..|:|.....::::.||.::.:......:..|...|..|||.:.|.:....:|
 Worm   263 QTDYLSKVLDYIDGRAYQDRVDYQFIYKNLAEACKVCNLDIDSPYDWELQKPEKTSKEP 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	80/288 (28%)
C27D8.1	NP_502428.1	Protein Kinases, catalytic domain	23..290	CDD:473864	80/286 (28%)