Protein Alignment CkIalpha and R13H9.6

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_500716.1
• Gene: R13H9.6 / 177277
• WormBaseID: WBGene00020072
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 295
• Identity: 90/295 - (30%)
• Similarity: 143/295 - (48%)
• Gaps: 57/295 - (19%)

  Fly    19 KYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILSGGVGFPRIRHHG 83
            ||:||..:|.|.:|.:|..:.:...|:.|||.|.|.|....||.:..:.:    |....:.||..
 Worm    23 KYKVIALLGKGGYGAVYSVLRLSDMEKFAIKCEKATAGKKVLLMDCNVMK----GATQIKSRHFS 83

  Fly    84 K-------EKNFNTLVMDLLGPSLEDLFNFCTRH------FTIKTVLMLVDQMIGRLEYIHLKCF 135
            .       :..||.:||.|:|.:|.||     |.      ||:.|.|....|.:..:|::|...:
 Worm    84 TVLDRANVKDRFNFIVMKLIGKNLWDL-----RQDRGDGKFTMGTSLKAASQCLVSIEHLHSFGY 143

  Fly   136 IHRDIKPDNFLMGIGRHCNK---LFLIDFGLAKKFRDPHTRHHIVYREDKNL---------TGTA 188
            :||||||.||..| .:..|:   :|::||||.        |.::...|.|:|         .||.
 Worm   144 LHRDIKPGNFAAG-RKESNEHHVIFMLDFGLC--------REYVKRAEGKDLRAARTTAPFRGTT 199

  Fly   189 RYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKK--MSTPIEV- 250
            |||.:.:.|..:|||:||:||..|:::.:..|.|||:.:||:.:    ||:.:.|  :.|..::
 Worm   200 RYAPLASMLQQDQSRKDDIESWLYMVVEWTSGGLPWRKLKAHDR----EKVLQYKQDLRTKPDIL 260

  Fly   251 -----LCKGSPAEFSMYLNYCRSLRFEEQPDYMYL 280
                 ||  ...||:..|.|..:|.:...|||.::
 Worm   261 DDFLFLC--PKKEFTRILKYLDTLGYYAVPDYKFI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	90/295 (31%)
R13H9.6	NP_500716.1	Protein Kinases, catalytic domain	23..296	CDD:473864	90/295 (31%)