Protein Alignment CkIalpha and TTBK2

DIOPT Version :9

• Sequence 1: NP_001162737.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: XP_005254228.1
• Gene: TTBK2 / 146057
• HGNCID: 19141
• Length: 1250
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 86/235 - (36%)
• Similarity: 119/235 - (50%)
• Gaps: 27/235 - (11%)

  Fly    83 GKEKNFNTLVMDLLGPSLEDLFNFCTR-HFTIKTVLMLVDQMIGRLEYIHLKCFIHRDIKPDNFL 146
            |:...||.:||.|.|.:|.||....:| .|||.|.|.|..|::..:|.||...|:||||||.||.
Human    90 GRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFA 154

  Fly   147 MG-IGRHCNKLFLIDFGLAKKF-------RDPHTRHHIVYREDKNLTGTARYASINAHLGIEQSR 203
            || ....|.|.:::|||||::|       |.|        |......||.||||||||...|..|
Human   155 MGRFPSTCRKCYMLDFGLARQFTNSCGDVRPP--------RAVAGFRGTVRYASINAHRNREMGR 211

  Fly   204 RDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKMSTPIEVLCKGSPAEFSMYLNYCRS 268
            .||:.||.|:::.|..|.|||:.:|..      |::...|......::.|..|.|||::|::..|
Human   212 HDDLWSLFYMLVEFVVGQLPWRKIKDK------EQVGSIKERYDHRLMLKHLPPEFSIFLDHISS 270

  Fly   269 LRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKT 308
            |.:..:|||..|..:|....:|........:||    :||
Human   271 LDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDW----EKT 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_001162737.1	PKc_like	19..284	CDD:304357	80/209 (38%)
		Pkinase_Tyr	23..284	CDD:285015	80/209 (38%)
TTBK2	XP_005254228.1	PKc_like	75..287	CDD:304357	80/210 (38%)
		SPS1	78..>267	CDD:223589	74/190 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810