DRSC/TRiP Functional Genomics Resources

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Protein Alignment CkIalpha and CSNK1G3

DIOPT Version :9

Sequence 1:NP_001162737.1 Gene:CkIalpha / 32221 FlyBaseID:FBgn0015024 Length:337 Species:Drosophila melanogaster
Sequence 2:XP_016864546.1 Gene:CSNK1G3 / 1456 HGNCID:2456 Length:481 Species:Homo sapiens


Alignment Length:353 Identity:164/353 - (46%)
Similarity:226/353 - (64%) Gaps:38/353 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 IIVGGKYRVIRKIGSGSFGDIYL-------------------------GMSIQSGEEVAIKMESA 53
            ::||..:||.:|||.|:||::.|                         |.::.:.|.||||:|..
Human    37 LMVGPNFRVGKKIGCGNFGELRLDQREKPEGCQGTSASLICDFRLCAQGKNLYTNEYVAIKLEPM 101

  Fly    54 HARHPQLLYEAKLYRILSGGVGFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTVLM 118
            .:|.|||..|.:.|:.|..|.|.|::.:.|....:|.:|::||||||||||:.|.|.|::|||||
Human   102 KSRAPQLHLEYRFYKQLGSGDGIPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFSLKTVLM 166

  Fly   119 LVDQMIGRLEYIHLKCFIHRDIKPDNFLMGIGRHCNK----LFLIDFGLAKKFRDPHTRHHIVYR 179
            :..|:|.|:||:|.|..|:||:||:|||  |||..||    :.:|||||||::.||.|:.||.||
Human   167 IAIQLISRMEYVHSKNLIYRDVKPENFL--IGRPGNKTQQVIHIIDFGLAKEYIDPETKKHIPYR 229

  Fly   180 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKM 244
            |.|:|||||||.|||.|||.|||||||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.
Human   230 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 294

  Fly   245 STPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTH 309
            :|||||||:..|.|.:.||.|.|.|.|.|:|||.|||:||..||....:.:||.|||...:..|.
Human   295 ATPIEVLCENFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRKGYMFDYEYDWIGKQLPTP 359

  Fly   310 QG--QPNPAI-----LLEQLDKDKEKQN 330
            .|  |.:||:     ..:..||.::.:|
Human   360 VGAVQQDPALSSNREAHQHRDKMQQSKN 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CkIalphaNP_001162737.1 PKc_like 19..284 CDD:304357 145/293 (49%)
Pkinase_Tyr 23..284 CDD:285015 143/289 (49%)
CSNK1G3XP_016864546.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1164
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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