Protein Alignment CkIalpha and Csnk1g2

DIOPT Version :10

• Sequence 1: NP_511140.1
• Gene: CkIalpha / 32221
• FlyBaseID: FBgn0015024
• Length: 337
• Species: Drosophila melanogaster
• Sequence 2: NP_598763.1
• Gene: Csnk1g2 / 103236
• MGIID: 1920014
• Length: 442
• Species: Mus musculus
• Alignment Length: 348
• Identity: 160/348 - (45%)
• Similarity: 223/348 - (64%)
• Gaps: 29/348 - (8%)

  Fly    14 IIVGGKYRVIRKIGSGSFGDIYLGMSIQSGEEVAIKMESAHARHPQLLYEAKLYRILS------G 72
            ::||..:||.:|||.|:||::.||.::.:.|.||||:|...:|.|||..|.:.|:.||      .
Mouse    40 LMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLSTTGEADS 104

  Fly    73 GV---------------------GFPRIRHHGKEKNFNTLVMDLLGPSLEDLFNFCTRHFTIKTV 116
            |.                     |.|::.:.|....:|.:|::||||||||||:.|.|.||:|||
Mouse   105 GTGPALLGQQWLRTPSMDVSFAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDRTFTLKTV 169

  Fly   117 LMLVDQMIGRLEYIHLKCFIHRDIKPDNFLMGI--GRHCNKLFLIDFGLAKKFRDPHTRHHIVYR 179
            ||:..|:|.|:||:|.|..|:||:||:|||:|.  .:..:.:.:|||||||::.||.|:.||.||
Mouse   170 LMIAIQLITRMEYVHTKSLIYRDVKPENFLVGRPGSKRQHSIHIIDFGLAKEYIDPETKKHIPYR 234

  Fly   180 EDKNLTGTARYASINAHLGIEQSRRDDMESLGYVMMYFNRGVLPWQGMKANTKQQKYEKISEKKM 244
            |.|:|||||||.|||.|||.|||||||:|:||::.|||.||.|||||:||:|.:::|:||.:.|.
Mouse   235 EHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKR 299

  Fly   245 STPIEVLCKGSPAEFSMYLNYCRSLRFEEQPDYMYLRQLFRILFRTLNHQYDYIYDWTMLKQKTH 309
            :|||||||:..|.|.:.||.|.|.|.|.|:|||.|||:||..||....:.:||.|||......|.
Mouse   300 ATPIEVLCESFPEEMATYLRYVRRLDFFEKPDYDYLRKLFTDLFDRSGYVFDYEYDWAGKPLPTP 364

  Fly   310 QGQPNPAILLEQLDKDKEKQNGK 332
            .|..:|.:..:...:||.:.:.|
Mouse   365 IGTVHPDVPSQPPHRDKAQLHTK 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CkIalpha	NP_511140.1	Protein Kinases, catalytic domain	19..284	CDD:473864	143/293 (49%)
Csnk1g2	NP_598763.1	STKc_CK1_gamma	45..359	CDD:271028	152/313 (49%)
		CK1gamma_C	359..412	CDD:463640	6/29 (21%)