Protein Alignment Tomosyn and Stxbp6

DIOPT Version :10

• Sequence 1: NP_727628.3
• Gene: Tomosyn / 32217
• FlyBaseID: FBgn0030412
• Length: 1470
• Species: Drosophila melanogaster
• Sequence 2: NP_001178801.1
• Gene: Stxbp6 / 362734
• RGDID: 1306117
• Length: 210
• Species: Rattus norvegicus
• Alignment Length: 218
• Identity: 60/218 - (27%)
• Similarity: 89/218 - (40%)
• Gaps: 49/218 - (22%)

  Fly  1272 LDTDFLPLMELSFQTKCKQGIVDPMLSIWGQQIIVHEDTTQISKIFCFSHKGHGLYMASPTEIQK 1336
            ||...|..:::..:||.|    .|.|:..||    .|..|.|    |.|........||.|::::
  Rat    15 LDERMLGAVQVKRRTKKK----IPFLATGGQ----GEYLTYI----CLSVTNKKPTQASITKVKQ 67

  Fly  1337 FTISSEF---CQFILEMMGELYTVHEMPEQPKEGF---FKGLFGGGAK----------------- 1378
            |..|:.|   .|::||.:.::..:.  |.:....|   |:..|.....
  Rat    68 FEGSTSFVRRSQWMLEQLRQVNGID--PNRDSAEFDLLFENAFDQWVASTASEKCTFFQILHHTC 130

  Fly  1379 ---LLDREELFGEQSGKPNRSVARHIPGPNLEQLGQRASTAASEISRAHQLAMERGEKLNLLEER 1440
               |.||:..|.....|        |.|.| ..|...|.:..|.:.:|.|...||||:|...||:
  Rat   131 QRYLTDRKPEFINCQSK--------IMGGN-SILHSAADSVTSAVQKASQALNERGERLGRAEEK 186

  Fly  1441 AERMANTAQDFSGTAHQLMLKYK 1463
            .|.|.|:||.|:.|||:|.:|:|
  Rat   187 TEDMKNSAQQFAETAHKLAMKHK 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tomosyn	NP_727628.3	WD40	<41..257	CDD:441893
		WD40 repeat	95..133	CDD:293791
		WD40 repeat	138..184	CDD:293791
		WD40 repeat	192..226	CDD:293791
		LLGL	268..376	CDD:462446
		R-SNARE_STXBP5_6	1403..1463	CDD:277226	25/59 (42%)
Stxbp6	NP_001178801.1	PH-STXBP6	2..131	CDD:270200	28/129 (22%)
		R-SNARE_STXBP6	149..210	CDD:277245	26/62 (42%)