Protein Alignment CG11085 and NKX6-2

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_796374.2
• Gene: NKX6-2 / 84504
• HGNCID: 19321
• Length: 277
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 62/225 - (27%)
• Similarity: 97/225 - (43%)
• Gaps: 58/225 - (25%)

  Fly    66 HDESSVESCL--SATRGPGS---------------GTGSG-----GGGGGGGGGGVASG---LSA 105
            |:.:.:::.|  .|.:||..               ||..|     |...|..|||:..|   |:.
Human    20 HNMAEMKTSLFPYALQGPAGFKAPALGGLGAQLPLGTPHGISDILGRPVGAAGGGLLGGLPRLNG 84

  Fly   106 AAAAAGVAAGLLAAAASG-------------------ANGD--RDANGGSGPGSGGGTSGGYAEH 149
            .|::|||..|..||.|.|                   ..|.  ||.. .:||...||.
Human    85 LASSAGVYFGPAAAVARGYPKPLAELPGRPPIFWPGVVQGAPWRDPR-LAGPAPAGGV------- 141

  Fly   150 KLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTK 214
               |.|.|:|...|.| |:..|:..||:.|...|||:..:|:.:|.:|.::|:|||.|:||||||
Human   142 ---LDKDGKKKHSRPT-FSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 202

  Fly   215 WKRQNQLRLEQLRHQATMEKDFVVQDGGGA 244
            |::::.:.:...:.:...:.:.:...|..|
Human   203 WRKRHAVEMASAKKKQDSDAEKLKVGGSDA 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	24/52 (46%)
NKX6-2	NP_796374.2	Repressor domain. /evidence=ECO:0000250|UniProtKB:D3Z4R4	89..142		15/63 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..155		10/33 (30%)
		Homeobox	151..204	CDD:306543	24/53 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		2/23 (9%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910