DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and En1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_001056699.4	Gene:	En1 / 685360	RGDID:	1595088	Length:	409	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	65/218 - (29%)
Similarity:	95/218 - (43%)	Gaps:	62/218 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 ATRGP--GSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDRDANGGSG--PG 137
            |..||  ||...:..|.|....|..|   :||||||..||..:||||:.|:...|:.||||  .|
  Rat   190 ANCGPPDGSQPATAVGAGASKAGNPA---AAAAAAAAAAAAAVAAAAAAASKPSDSGGGSGGSAG 251

  Fly   138 SGGGTSGGYAEH----------------------------------------------KLQLSKS 156
            |.|.....:.||                                              ||:..|:
  Rat   252 SPGAQGAKFPEHNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPRTRKLKKKKN 316

  Fly   157 GRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKR---- 217
            .::.:|.|||||..||..|:.:|:..:|::...|..:|:.|:|:|:|:|.|:||:|.|.|:
  Rat   317 EKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKRAKIKKATGI 381

  Fly   218 QNQLRLEQL-----RHQATMEKD 235
            :|.|.|..:     .|..|..:|
  Rat   382 KNGLALHLMAQGLYNHSTTTVQD 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	22/52 (42%)
En1	XP_001056699.4	Homeobox	323..377	CDD:395001	22/53 (42%)
En1	XP_001056699.4	Engrail_1_C_sig	378..408	CDD:402244	6/27 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910