DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11085 and Tlx2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001165596.1	Gene:	Tlx2 / 680117	RGDID:	1595506	Length:	284	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	72/235 - (30%)
Similarity:	100/235 - (42%)	Gaps:	71/235 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LLSHHHRRFTHHDESS--VESCLSATRGPGSGTGSGG-GGGGGGGGGVASGLSAAAAAAGVAAGL 116
            :|:.||  ..||:..|  ::..||....||.|.|.|. |...|.....:||....:..|  .||.
  Rat     5 VLAPHH--LPHHEPISFGIDQILSGPEPPGGGLGPGQVGQSQGESAAFSSGFHGTSGYA--PAGS 65

  Fly   117 LAAAASGANGDRDANGGSGPG--------------------------SGGGTSGGYAEHKLQLSK 155
            ||:...|:        |.|||                          ||.|..||.|........
  Rat    66 LASLPRGS--------GVGPGGVIRVPAHRPVPVPPPSGAAPAVAGPSGLGGPGGLAGLTFPWMD 122

  Fly   156 SGRK----------------------------PRRR--RTAFTHAQLAYLERKFRCQKYLSVADR 190
            |||:                            |:|:  ||:|:.:|:..|||:|..||||:.|:|
  Rat   123 SGRRFAKDRLTAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAER 187

  Fly   191 SDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQA 230
            :.:|:.|.:::.|||||:|||||||:||.....|..||:|
  Rat   188 AALAKALRMTDAQVKTWFQNRRTKWRRQTAEEREAERHRA 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	27/54 (50%)
Tlx2	NP_001165596.1	Homeobox	160..213	CDD:278475	27/52 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000