Protein Alignment CG11085 and NKX1-1

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 92/306 - (30%)
• Similarity: 122/306 - (39%)
• Gaps: 83/306 - (27%)

  Fly    23 DSELELSNDDSDIDIEDRSTPDSTAAGCQQELLLSHHHRRFTHHDESSVESCLSATRGPGSGTGS 87
            ||..|:.:|:.|   ::...|::.||                                .|:....
Human   185 DSGDEVPDDEDD---DEDEAPETEAA--------------------------------RGAEEAR 214

  Fly    88 GGGGGGGGGGGVASGLSAAAAAAGVAAGLLAA--------AASGANGDRDANGGSGPGSGGGTSG 144
            |||||.|..|....|.:...|:.|......||        .|.|..|...|.||:|....|..:.
Human   215 GGGGGLGARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATA 279

  Fly   145 GYAEHKL--QLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTW 207
            ...:.|.  ..|||| ||||.|||||:.||..||.||:..:||||.:|.::|.:|:|:|||||.|
Human   280 AKPKRKRTGSDSKSG-KPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIW 343

  Fly   208 YQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAG-------GLGCCPSGLS---------- 255
            :||||||||:||.            ..|.....|||.|       |.| .|.|||
Human   344 FQNRRTKWKKQNP------------GADTSAPTGGGGGPGPGAGPGTG-LPGGLSPLSPSPPMGA 395

  Fly   256 -------SSFSAAAAAAAAASNPCNFLTSAAAAAIFRNVGYVHGCP 294
                   :.:.|........:....||:|.|..:.|......:|.|
Human   396 PLGMHGPAGYPAHGPGGLVCAAQLPFLSSPAVLSPFVLGSQTYGAP 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	31/52 (60%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	31/51 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810