Protein Alignment CG11085 and PITX3

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_005020.1
• Gene: PITX3 / 5309
• HGNCID: 9006
• Length: 302
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 70/292 - (23%)
• Similarity: 100/292 - (34%)
• Gaps: 108/292 - (36%)

  Fly   102 GLSAAAAAAGVAAGLLAAAA-------SGANGDR--DANGGSGPGSGGGTSGGYAEHKLQLSKSG 157
            ||.:.|.|...|..|..|..       .|..|..  |:...|....||....|..:
Human     4 GLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEKASASLPGGSPEDGSLK--------- 59

  Fly   158 RKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQ---- 218
            :|.||:||.||..||..||..|:..:|..::.|.::|...||:|.:|:.|::|||.||:::
Human    60 KKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERSQ 124

  Fly   219 --------------------------------------------------NQLRLEQLRHQ---- 229
                                                              |.:.:..|..|
Human   125 QAELCKGSFAAPLGGLVPPYEEVYPGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFS 189

  Fly   230 ------ATMEKDFVVQDG-----GGAGGLGCCPSGLSSS-----------FSAAAAAAAAAS--- 269
                  |:|........|     |...|||..|.||:.:           .|||||||||||
Human   190 PPSSIAASMVPSAAAAPGTVPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPY 254

  Fly   270 ---NPCNFLTSAAAAAIFRNVGY----VHGCP 294
               :|||...::......::..:    |||.|
Human   255 VYRDPCNSSLASLRLKAKQHASFSYPAVHGPP 286

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	21/52 (40%)
PITX3	NP_005020.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		20/75 (27%)
		Homeobox	66..119	CDD:395001	22/52 (42%)
		OAR	258..275	CDD:397759	3/16 (19%)
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	262..275		0/12 (0%)
		Nuclear localization signal. /evidence=ECO:0000255	268..272		0/3 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910