Protein Alignment CG11085 and NKX6-1

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_006159.2
• Gene: NKX6-1 / 4825
• HGNCID: 7839
• Length: 367
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 64/255 - (25%)
• Similarity: 95/255 - (37%)
• Gaps: 91/255 - (35%)

  Fly    73 SCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLA------------------- 118
            :.|.:....||.:.|............|:..:||||||...|||||
Human   113 AALPSASPSGSSSSSSSSASASSASAAAAAAAAAAAAASSPAGLLAGLPRFSSLSPPPPPPGLYF 177

  Fly   119 ---AAASGANGD-------------------------RDANGGSGPGSGGGTSGGYAEHKLQLSK 155
               |||..|.|.                         |||.....|..|          .:.|.|
Human   178 SPSAAAVAAVGRYPKPLAELPGRTPIFWPGVMQSPPWRDARLACTPHQG----------SILLDK 232

  Fly   156 SGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQ 220
            .|::...|.| |:..|:..||:.|...|||:..:|:.:|.:|.::|:|||.|:|||||||::::.
Human   233 DGKRKHTRPT-FSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKHA 296

  Fly   221 LRL-----------EQLRHQATMEK---DF------------VVQ-------DGGGAGGL 247
            ..:           |:|:..:..|:   |:            :.|       ..||.|||
Human   297 AEMATAKKKQDSETERLKGASENEEEDDDYNKPLDPNSDDEKITQLLKKHKSSSGGGGGL 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	24/52 (46%)
NKX6-1	NP_006159.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..133		4/19 (21%)
		Repressor domain. /evidence=ECO:0000250	102..268		40/165 (24%)
		Homeobox	239..293	CDD:395001	25/54 (46%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	294..367		10/63 (16%)
		Involved in DNA-binding. /evidence=ECO:0000250	306..367		10/51 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910