DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11085 and DBX2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001004329.2	Gene:	DBX2 / 440097	HGNCID:	33186	Length:	339	Species:	Homo sapiens

Alignment Length:	193	Identity:	61/193 - (31%)
Similarity:	78/193 - (40%)	Gaps:	43/193 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ASGLSAAAAAAGV--AAGLLAAAASGAN------GDRDAN------------------------G 132
            |..:|.|.|..|.  |..:|:.:|..|.      ||||..                        |
Human    89 AEQVSPAGAPYGTRWAFQVLSPSADSARLPGRAPGDRDCTFQPSAPAPSKPFLLSTPPFYSACCG 153

  Fly   133 GSGPGSGGGTSGGYAEHKLQL--SKSGRKPRR---RRTAFTHAQLAYLERKFRCQKYLSVADRSD 192
            ||.......|:....|..|.|  ..|..|.||   ||..|:..|...||:.|:.|||:|..||..
Human   154 GSCRRPASSTAFPREESMLPLLTQDSNSKARRGILRRAVFSEDQRKALEKMFQKQKYISKTDRKK 218

  Fly   193 VAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAGGLGC---CPS 252
            :|..|.|.|:|||.|:||||.||:  |....|.|.::...|.. :.:|......||.   |||
Human   219 LAINLGLKESQVKIWFQNRRMKWR--NSKEKEVLSNRCIQEVG-LQEDPLSRSALGFPSPCPS 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	26/52 (50%)
DBX2	NP_001004329.2	Homeobox	189..242	CDD:278475	26/52 (50%)
DBX2	NP_001004329.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	282..318
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810