DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and isl1b

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001002043.1	Gene:	isl1b / 415131	ZFINID:	ZDB-GENE-040624-1	Length:	323	Species:	Danio rerio

Alignment Length:	168	Identity:	39/168 - (23%)
Similarity:	60/168 - (35%)	Gaps:	42/168 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 EHKLQLSKSGRKPR-----RRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTW 207
            |.|..||.|..:.|     |.||..:..||..|:..:..........:..:.|...||...::.|
Zfish   155 EIKSTLSWSSMQRRSERATRVRTVLSETQLCMLQTCYTANPRPDALMKEQLVEMTGLSPRVIRVW 219

  Fly   208 YQNRRTKWK------RQNQLRLEQLRHQATME-----------------------KDFVVQDGGG 243
            :||:|.|.|      |..|.:||  .|..:.|                       .||::|:...
Zfish   220 FQNKRCKDKKRSLTMRHTQKQLE--GHLVSEEPLLLVSTESQDSDVMISPPWKLLTDFILQNEAE 282

  Fly   244 AGGLGCCPSGLS---SSFSAAAAAAAAASNPCNFLTSA 278
            ....   |..||   ....:|.:..|:.|:..|.||::
Zfish   283 HRSF---PQMLSLPTEGPCSAGSEVASVSDTANSLTAS 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	13/52 (25%)
isl1b	NP_001002043.1	LIM1_Isl	19..73	CDD:188752
		LIM	81..135	CDD:295319
		HOX	174..228	CDD:197696	14/53 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910