DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and HOXD1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_078777.1	Gene:	HOXD1 / 3231	HGNCID:	5132	Length:	328	Species:	Homo sapiens

Alignment Length:	172	Identity:	55/172 - (31%)
Similarity:	75/172 - (43%)	Gaps:	32/172 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PG-SGTGSGGGGG----------GGGGGGVASGL--SAAAAAAGVAAGLLAAAASGANG---DRD 129
            || .|..:..||.          .|||..:.||.  .||....|.....|.|:|.|..|   ...
Human   118 PGVLGRAADDGGSHVHYATSAVFSGGGSFLLSGQVDYAAFGEPGPFPACLKASADGHPGAFQTAS 182

  Fly   130 ANGGSGPGSGGGTSG--------GYAEHKLQLSKSGR-------KPRRR-RTAFTHAQLAYLERK 178
            ...|:.|.|....||        .:.:.|...||.|:       .|... ||.|:..||..||::
Human   183 PAPGTYPKSVSPASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKE 247

  Fly   179 FRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQ 220
            |...|||:.|.|.::|..|:|::||||.|:||||.|.|::.:
Human   248 FHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKRER 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	26/53 (49%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeobox	233..285	CDD:278475	26/51 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	305..328
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910