DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11085 and HOXB6

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:XP_011523029.1 Gene:HOXB6 / 3216 HGNCID:5117 Length:288 Species:Homo sapiens


Alignment Length:197 Identity:55/197 - (27%)
Similarity:74/197 - (37%) Gaps:55/197 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    77 ATRGPGSGTGSGGGGG-----GGGGGGVASGLSAAAAAAGVAAGLLAAAASGAN----------- 125
            |..|||.|...|....     .|||.|.|:......|.|.......|.|.|||:           
Human   105 APYGPGPGQDKGFATSSYYPPAGGGYGRAAPCDYGPAPAFYREKESACALSGADEQPPFHPEPRK 169

  Fly   126 ----------GDRDANGGSGP------------GSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFT 168
                      |:.:....|.|            .|..|.||                ||.|..:|
Human   170 SDCAQDKSVFGETEEQKCSTPVYPWMQRMNSCNSSSFGPSG----------------RRGRQTYT 218

  Fly   169 HAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQ-LRLEQLRHQATM 232
            ..|...||::|...:||:...|.::|..|.|:|.|:|.|:||||.|||:::: |...||..:...
Human   219 RYQTLELEKEFHYNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKKESKLLSASQLSAEEEE 283

  Fly   233 EK 234
            ||
Human   284 EK 285

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475 21/52 (40%)
HOXB6XP_011523029.1 Homeobox 214..266 CDD:278475 21/51 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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