DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and HOXB3

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_016880049.1	Gene:	HOXB3 / 3213	HGNCID:	5114	Length:	578	Species:	Homo sapiens

Alignment Length:	218	Identity:	68/218 - (31%)
Similarity:	88/218 - (40%)	Gaps:	56/218 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 RSTPDSTAAGCQQELLLSHHHRRFTHHDESSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLS 104
            :|.|.....|....|.    .:.|....||...|.|. ...||:..|.|||||||||||
Human   258 KSGPPKCGPGTNSTLT----KQIFPWMKESRQTSKLK-NNSPGTAEGCGGGGGGGGGGG------ 311

  Fly   105 AAAAAAGVAAGLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTH 169
                                      :||||.|.|||..|..:......||      |.|||:|.
Human   312 --------------------------SGGSGGGGGGGGGGDKSPPGSAASK------RARTAYTS 344

  Fly   170 AQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEK 234
            |||..||::|...:||....|.::|..|||||.|:|.|:||||.|:|:..:.:
Human   345 AQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQNRRMKYKKDQKAK------------ 397

  Fly   235 DFVVQDGGGAGGLGCCPSGLSSS 257
             .:....||....|..|..:.|:
Human   398 -GLASSSGGPSPAGSPPQPMQST 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	27/52 (52%)
HOXB3	XP_016880049.1	Homeobox	339..391	CDD:278475	27/51 (53%)
HOXB3	XP_016880049.1	DUF4074	513..576	CDD:290032
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910