DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and HOXB2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_002136.1	Gene:	HOXB2 / 3212	HGNCID:	5113	Length:	356	Species:	Homo sapiens

Alignment Length:	180	Identity:	60/180 - (33%)
Similarity:	78/180 - (43%)	Gaps:	47/180 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 SAAAAAAGVAAGLLAAAASGANGDRDANGGSG-PGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAF 167
            |.:|.:...||..:.|:..|:..|     |.| |.:|||.:                 ||.|||:
Human   108 SQSATSPSPAASAVPASGVGSPAD-----GLGLPEAGGGGA-----------------RRLRTAY 150

  Fly   168 THAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATM 232
            |:.||..||::|...|||....|.::|..|:|:|.|||.|:||||.|.|||.|.|
Human   151 TNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHR---------- 205

  Fly   233 EKDFVVQDGGGAGGLGCCPSGLSSSFSAAAAAAAAASNPCNFLTSAAAAA 282
                ...||..|     ||..|......|...||:...|     ||:.||
Human   206 ----EPPDGEPA-----CPGALEDICDPAEEPAASPGGP-----SASRAA 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	26/52 (50%)
HOXB2	NP_002136.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	39..142		12/38 (32%)
		Antp-type hexapeptide	94..99
		Homeobox	147..199	CDD:278475	26/51 (51%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..240		18/66 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910