Protein Alignment CG11085 and HOXA11

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_005514.1
• Gene: HOXA11 / 3207
• HGNCID: 5101
• Length: 313
• Species: Homo sapiens
• Alignment Length: 214
• Identity: 62/214 - (28%)
• Similarity: 90/214 - (42%)
• Gaps: 41/214 - (19%)

  Fly    46 TAAGCQQELLLSHHHRRFTHHDESSVESCLSATRGPGS--------------GTGSG-------G 89
            :|||...::|.......: ||...:|.|...:|.|...              ||...       |
Human    98 SAAGVPGDVLAKSSANVY-HHPTPAVSSNFYSTVGRNGVLPQAFDQFFETAYGTPENLASSDYPG 161

  Fly    90 GGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGD--------------RDANGGSGPGSGG 140
            ......|...|:..|||||||...|...:::.||..|.              |.....|.|.|
Human   162 DKSAEKGPPAATATSAAAAAAATGAPATSSSDSGGGGGCRETAAAAEEKERRRRPESSSSPES-- 224

  Fly   141 GTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVK 205
              |.|:.|.|.. ..||::.|::|..:|..|:..|||:|....|::...|..::..|||::.|||
Human   225 --SSGHTEDKAG-GSSGQRTRKKRCPYTKYQIRELEREFFFSVYINKEKRLQLSRMLNLTDRQVK 286

  Fly   206 TWYQNRRTKWKRQNQLRLE 224
            .|:||||.|.|:.|:.||:
Human   287 IWFQNRRMKEKKINRDRLQ 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	22/55 (40%)
HOXA11	NP_005514.1	DUF3528	25..153	CDD:432284	12/55 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..246		25/96 (26%)
		Homeodomain	242..298	CDD:459649	22/55 (40%)