DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11085 and HOXA10

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:NP_061824.3 Gene:HOXA10 / 3206 HGNCID:5100 Length:410 Species:Homo sapiens


Alignment Length:223 Identity:64/223 - (28%)
Similarity:92/223 - (41%) Gaps:61/223 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 PDSTAAGCQQELLLSHHHRRFTHHDESSVESCLSATRGPGSGTGSGGGGGGGGGGG--------- 98
            ||..|.|....:.:..:.|             ||...|...|.||||||....|.|         
Human   197 PDGCALGTSSGVPVPGYFR-------------LSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGR 248

  Fly    99 -------VASGLSAAAAAAGVAAG------LLAAAASGANGDRDANGGSGPG------------- 137
                   :||| ||.||....|..      |...:..|:.||.:|:..|...             
Human   249 GFDLPPALASG-SADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKA 312

  Fly   138 -----SGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETL 197
                 |.|.:.|..|.:.| .:|||||   :|..:|..|...||::|....||:...|.:::.::
Human   313 SPEKDSLGNSKGENAANWL-TAKSGRK---KRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSV 373

  Fly   198 NLSETQVKTWYQNRRTKWK---RQNQLR 222
            :|::.|||.|:||||.|.|   |:|::|
Human   374 HLTDRQVKIWFQNRRMKLKKMNRENRIR 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475 19/52 (37%)
HOXA10NP_061824.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 89..158
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 221..339 34/122 (28%)
Homeobox 339..392 CDD:278475 19/52 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.