DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and HOXA3

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001371264.1	Gene:	HOXA3 / 3200	HGNCID:	5104	Length:	443	Species:	Homo sapiens

Alignment Length:	197	Identity:	51/197 - (25%)
Similarity:	74/197 - (37%)	Gaps:	66/197 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   121 ASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYL 185
            :|.::|:..|...|.||....                   :|.|||:|.|||..||::|...:||
Human   171 SSSSSGESCAGDKSPPGQASS-------------------KRARTAYTSAQLVELEKEFHFNRYL 216

  Fly   186 SVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGG-------- 242
            ....|.::|..|||:|.|:|.|:||||.|:|:..:            .|..:...||
Human   217 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK------------GKGMLTSSGGQSPSRSPV 269

  Fly   243 --GAGG---------------------LGCCPSGL----SSSFSAAAAAAAAASNPCNFLTSAAA 280
              ||||                     ....|.|.    .:|:.|:..:.|....|....|:|.|
Human   270 PPGAGGYLNSMHSLVNSVPYEPQSPPPFSKPPQGTYGLPPASYPASLPSCAPPPPPQKRYTAAGA 334

  Fly   281 AA 282
            .|
Human   335 GA 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	26/52 (50%)
HOXA3	NP_001371264.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	75..147
		Antp-type hexapeptide	155..160
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..196		7/43 (16%)
		Homeobox	195..248	CDD:395001	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	247..338		18/102 (18%)
		DUF4074	378..441	CDD:404218
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	400..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910