Protein Alignment CG11085 and TLX2

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_057254.1
• Gene: TLX2 / 3196
• HGNCID: 5057
• Length: 284
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 73/225 - (32%)
• Similarity: 101/225 - (44%)
• Gaps: 51/225 - (22%)

  Fly    55 LLSHHHRRFTHHDESS--VESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLL 117
            :|..|:  ..||:..|  ::..||....||.|.|.|.||.|.|..|..||....|:..|.|..|.
Human     5 MLGPHN--LPHHEPISFGIDQILSGPETPGGGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLA 67

  Fly   118 AAAASG---------------------ANGDRDANGGSGPGSGGGTSG----------GYAEHKL 151
            ....|.                     |.|.....|.||.|..||.:|          .:|:.:|
Human    68 PLPGSSGVGPGGVIRVPAHRPLPVPPPAGGAPAVPGPSGLGGAGGLAGLTFPWMDSGRRFAKDRL 132

  Fly   152 QLSKS-------------GRKPRRR---RTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLS 200
            ..:.|             .|.|.:|   ||:|:.:|:..|||:|..||||:.|:|:.:|:.|.::
Human   133 TAALSPFSGTRRIGHPYQNRTPPKRKKPRTSFSRSQVLELERRFLRQKYLASAERAALAKALRMT 197

  Fly   201 ETQVKTWYQNRRTKWKRQNQLRLEQLRHQA 230
            :.|||||:|||||||:||.....|..||:|
Human   198 DAQVKTWFQNRRTKWRRQTAEEREAERHRA 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	28/55 (51%)
TLX2	NP_057254.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		17/46 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	78..106		3/27 (11%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..166		6/26 (23%)
		Homeobox	160..213	CDD:278475	27/52 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.900