DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11085 and TLX1

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:XP_011538046.1 Gene:TLX1 / 3195 HGNCID:5056 Length:342 Species:Homo sapiens


Alignment Length:280 Identity:77/280 - (27%)
Similarity:105/280 - (37%) Gaps:105/280 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 LSHHHRRFTHHDESS--VESCLSA-----TRGPGS-------GTGS--GG----GGGG-----GG 95
            |..||....|.:..|  ::..|::     ..||.|       |.|.  ||    ||||     |.
Human     4 LGPHHLHPGHAEPISFGIDQILNSPDQGGCMGPASRLQDGEYGLGCLVGGAYTYGGGGSAAATGA 68

  Fly    96 GGGVASGLSAAAAAAGVAAGLLAAAASGANGDRDAN----GGSGPGSGGGTSGG----------- 145
            ||..|.|........|.|.|..|.:.....|..:.|    ||.|||.|||:|||           
Human    69 GGAGAYGTGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSSGGAGALSAAGVIR 133

  Fly   146 -------------------------------------------------YAEHKLQLSKS----- 156
                                                             |.:.:..::.|     
Human   134 VPAHRPLAGAVAHPQPLATGLPTVPSVPAMPGVNNLTGLTFPWMESNRRYTKDRFTVALSPFTVT 198

  Fly   157 --------GRKP---RRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQN 210
                    .|.|   ::.||:||..|:..||::|..||||:.|:|:.:|:.|.:::.|||||:||
Human   199 RRIGHPYQNRTPPKKKKPRTSFTRLQICELEKRFHRQKYLASAERAALAKALKMTDAQVKTWFQN 263

  Fly   211 RRTKWKRQNQLRLEQLRHQA 230
            |||||:||.....|..|.||
Human   264 RRTKWRRQTAEEREAERQQA 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475 27/52 (52%)
TLX1XP_011538046.1 Homeobox 216..269 CDD:278475 27/52 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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