Protein Alignment CG11085 and HLX

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_068777.1
• Gene: HLX / 3142
• HGNCID: 4978
• Length: 488
• Species: Homo sapiens
• Alignment Length: 365
• Identity: 75/365 - (20%)
• Similarity: 111/365 - (30%)
• Gaps: 137/365 - (37%)

  Fly    43 PDSTAAGCQQE---LLLSHHHRRFTHHDESSVES------------CLSATRGPGSGT------- 85
            |....||..|.   |..::||    ||.:...:.            ...|.:.|.|||
Human   101 PSEVPAGFPQRLSPLSAAYHH----HHPQQQQQQQQPQQQQPPPPPRAGALQPPASGTRVVPNPH 161

  Fly    86 GSGGGGGGGGGG---GVASGLSAAAAAAGVAAGLLAAAASGANGDRDAN---GGSGPGSG----- 139
            .||.........   |:...|||...........|....|...|.|.|.   .|..|.:|
Human   162 HSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPAGVHLSGLQPSAGQFFAS 226

  Fly   140 --------------GGTSGGYAEHKLQLSKSG---------------RKPRRRRTAFTHAQLAYL 175
                          ........:|:.|.:..|               ||....|..|::.|...|
Human   227 LDPINEASAILSPLNSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGL 291

  Fly   176 ERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRL----------------- 223
            |::|..|||::..||..:|..|.|::.|||.|:||||.||:...:.:.
Human   292 EKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGAP 356

  Fly   224 -----------------------------------------EQLRHQATMEK-----DFVVQDGG 242
                                                     |:..||.|:.|     ..:.....
Human   357 AADGEQDERSPSRSEGEAESESSDSESLDMAPSDTERTEGSERSLHQTTVIKAPVTGALITASSA 421

  Fly   243 GAGGLGCCPSGLSSSFSAAAAAAAAASNPCNFLTSAAAAA 282
            |:||   ...|..:|||.::|::.::|:     |||..|:
Human   422 GSGG---SSGGGGNSFSFSSASSLSSSS-----TSAGCAS 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	23/52 (44%)
HLX	NP_068777.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..173		11/58 (19%)
		Abdominal-A	227..>344	CDD:332641	29/116 (25%)
		Homeobox	279..332	CDD:306543	23/52 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	331..488		19/131 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900