DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and MNX1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_005506.3	Gene:	MNX1 / 3110	HGNCID:	4979	Length:	401	Species:	Homo sapiens

Alignment Length:	236	Identity:	81/236 - (34%)
Similarity:	98/236 - (41%)	Gaps:	76/236 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PG-SGTGSGGGGGGGGGGG-----------VASGLSAAAAAAGVAAGL----------------- 116
            || .|.|.||||.|||.||           .|:..:|||||.|:|.||
Human    94 PGFLGAGGGGGGTGGGHGGPHHHAHPGAAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAAL 158

  Fly   117 ---------LAAAASGANGDRDANGGSGPGSGG------------GTSGGYAEHKLQLSKSGR-- 158
                     .||||:...|...|...|.|...|            |......:..|:.|.:|.
Human   159 YGHPVYGYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMIL 223

  Fly   159 ----------------KPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTW 207
                            |.||.|||||..||..||.:|:..||||...|.:||.:|.|:|||||.|
Human   224 PKMPDFNSQAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIW 288

  Fly   208 YQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAGGLG 248
            :||||.||||..:.: ||...:|..:|       ||.||.|
Human   289 FQNRRMKWKRSKKAK-EQAAQEAEKQK-------GGGGGAG 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	30/52 (58%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..78
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..120		9/18 (50%)
		Homeobox	244..297	CDD:278475	30/52 (58%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	299..401		9/31 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910