DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and otx1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_571325.2	Gene:	otx1 / 30500	ZFINID:	ZDB-GENE-980526-400	Length:	323	Species:	Danio rerio

Alignment Length:	161	Identity:	45/161 - (27%)
Similarity:	74/161 - (45%)	Gaps:	28/161 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   138 SGGGTSG----------GYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSD 192
            :|.|.||          ||       ..:.||.||.||.||.:||..||..|...:|..:..|.:
Zfish    13 NGLGLSGAAMDLLHPSVGY-------PATPRKQRRERTTFTRSQLDILEALFAKTRYPDIFMREE 70

  Fly   193 VAETLNLSETQVKTWYQNRRTKWKRQNQ------LRLEQLRHQATMEKDFVVQDGGGAGGLGCCP 251
            ||..:||.|::|:.|::|||.|.::|.|      .|..:.:...|.|     ..|..:.|....|
Zfish    71 VALKINLPESRVQVWFKNRRAKCRQQQQSGSSTKTRPAKKKSSPTRE-----STGSESSGQFTPP 130

  Fly   252 SGLSSSFSAAAAAAAAASNPCNFLTSAAAAA 282
            :..|:..|::::::...:..|:..||.:..:
Zfish   131 AVSSAGSSSSSSSSTNNTGICSTSTSISTVS 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	22/52 (42%)
otx1	NP_571325.2	Homeobox	42..94	CDD:278475	22/51 (43%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	91..155		12/68 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	168..204
		TF_Otx	172..258	CDD:281521
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	239..277
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910