DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Lhx2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_006234134.1	Gene:	Lhx2 / 296706	RGDID:	71076	Length:	414	Species:	Rattus norvegicus

Alignment Length:	233	Identity:	61/233 - (26%)
Similarity:	94/233 - (40%)	Gaps:	37/233 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 QELLLSHHHRRFTHHDESSVESCLSATRGPGSGTGSGGGGGGG-----GGGGVASGLSAAAAAAG 111
            :.||...:...|.|.|.::..:..:|.:  .:|.||.|....|     |.|.|..|......:.|
  Rat   178 EALLQGEYPAHFNHADVAAAAAAAAAAK--SAGLGSAGANPLGLPYYNGVGTVQKGRPRKRKSPG 240

  Fly   112 VAAGLLAAAASGANGDRDANGGSGPGSGGGTSGGYAEH--KLQLSKSGRKPRRRRTAFTHAQLAY 174
            ..|.|.|..|:.:..:.|                 |||  :.|...|.:|.:|.||:|.|.||..
  Rat   241 PGADLAAYNAALSCNEND-----------------AEHLDRDQPYPSSQKTKRMRTSFKHHQLRT 288

  Fly   175 LERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQ 239
            ::..|.........|...:|:...|::..::.|:||.|.|::| |.||.|......|  .|..:|
  Rat   289 MKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR-NLLRQENTGVDKT--SDATLQ 350

  Fly   240 DGGGAGGLGCCPSGLSSSFSAAAAAAAAASNPCNFLTS 277
            .|        .|||.:|..|.|:.:.::.......|||
  Rat   351 TG--------TPSGPASELSNASLSPSSTPTTLTDLTS 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	15/52 (29%)
Lhx2	XP_006234134.1	LIM1_Lhx2	43..106	CDD:188853
		LIM2_Lhx2_Lhx9	119..177	CDD:188763
		COG5576	<255..386	CDD:227863	41/154 (27%)
		Homeobox	278..331	CDD:395001	15/52 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910