DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Alx4

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001100023.1	Gene:	Alx4 / 296511	RGDID:	1310201	Length:	399	Species:	Rattus norvegicus

Alignment Length:	237	Identity:	58/237 - (24%)
Similarity:	94/237 - (39%)	Gaps:	55/237 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 GGGGVASGLSAAAAA----------------AGVAAGLLAAAASGANGDRDANGGSGPGSGGGTS 143
            |.||..:.|.....|                .|:....|:...:||.|.:|..|...|.
  Rat   130 GSGGHNAALQVPCYAKESNLGEPELPPDSEPVGMDNSYLSVKETGAKGPQDRAGAEIPS------ 188

  Fly   144 GGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWY 208
               ...|.....|..|.||.||.||..||..||:.|:...|..|..|..:|...:|:|.:|:.|:
  Rat   189 ---PLEKTDSESSKGKKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARVQVWF 250

  Fly   209 QNRRTKWKRQNQL-RLEQLR----------------HQATMEKDFVVQDGGGAGGLGCC------ 250
            ||||.||:::.:. :::|:|                :.|.::....:.:.|.|..:..|
  Rat   251 QNRRAKWRKRERFGQMQQVRTHFSTAYELPLLTRAENYAQIQNPSWIGNNGAASPVPACVVPCDP 315

  Fly   251 -PSGLSSSFSAAAAAAAAASNPCNFLTSAAAAAIFRNVGYVH 291
             |:.:|..   |....:.||:..:||:.:.|.:   :||..|
  Rat   316 VPACMSPH---AHPPGSGASSVSDFLSVSGAGS---HVGQTH 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	22/52 (42%)
Alx4	NP_001100023.1	Homeobox	206..258	CDD:278475	22/51 (43%)
Alx4	NP_001100023.1	OAR	375..392	CDD:281777
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910