DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and GBX1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001092304.1	Gene:	GBX1 / 2636	HGNCID:	4185	Length:	363	Species:	Homo sapiens

Alignment Length:	154	Identity:	60/154 - (38%)
Similarity:	77/154 - (50%)	Gaps:	26/154 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SSVESCLSATRGPGSGT-----GSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDR 128
            ||.|..|.|:.|..:|:     ||||.....|      .|.::|...|        |..|.....
Human   186 SSDEEKLEASAGDPAGSEQEEEGSGGDSEDDG------FLDSSAGGPG--------ALLGPKPKL 236

  Fly   129 DANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDV 193
            ..:.|:|...|...:.|       ::..|.|.||||||||..||..||::|.|:||||:.:||.:
Human   237 KGSLGTGAEEGAPVTAG-------VTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQI 294

  Fly   194 AETLNLSETQVKTWYQNRRTKWKR 217
            |..|.|||.|||.|:||||.||||
Human   295 AHALKLSEVQVKIWFQNRRAKWKR 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	32/52 (62%)
GBX1	NP_001092304.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..31
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	128..265		25/99 (25%)
		Homeobox	264..317	CDD:306543	32/52 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910