DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11085 and Msx2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_037114.2	Gene:	Msx2 / 25483	RGDID:	3116	Length:	267	Species:	Rattus norvegicus

Alignment Length:	250	Identity:	79/250 - (31%)
Similarity:	108/250 - (43%)	Gaps:	75/250 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 SATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLA--------------AAASGA-- 124
            |...||....|.|.|.||..||.....:..::....|.| |::              .|::||
  Rat    13 SDEEGPAVLAGPGPGPGGAEGGAEERRVKVSSLPFSVEA-LMSDKKPPKESPAVPPDCASAGAVL 76

  Fly   125 -------NGDRDANGGSGP-------------GSGGGT-----SGGYAEHKLQLS---------K 155
                   :|.|||: ..||             .|..|.     .|.|:.....:|         |
  Rat    77 RPLLLPGHGVRDAH-SPGPLVKPFETASVKSENSEDGAPWIQEPGRYSPPPRHMSPTTCTLRKHK 140

  Fly   156 SGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQ 220
            :.|||   ||.||.:||..||||||.::|||:|:|::.:.:|||:|||||.|:||||.|.||..:
  Rat   141 TNRKP---RTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQE 202

  Fly   221 LRLEQLRHQATMEKDFVVQDGGGAGGLGCCPSGLSSSF----SAAAAAAAAASNP 271
            ..||:|:..|   |..:             |||.|..|    ...||:..:||.|
  Rat   203 AELEKLKMAA---KPML-------------PSGFSLPFPINSPLQAASIYSASYP 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	31/52 (60%)
Msx2	NP_037114.2	Homeobox	145..199	CDD:395001	32/56 (57%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000776
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910