Protein Alignment CG11085 and EN2

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_001418.2
• Gene: EN2 / 2020
• HGNCID: 3343
• Length: 333
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 77/297 - (25%)
• Similarity: 115/297 - (38%)
• Gaps: 106/297 - (35%)

  Fly    41 STPDSTAAGCQQELLL--------SHHH-RRFTHHDESSVESCLSAT--RGPGSGT---GSGGG- 90
            |:|.....|.::.|:|        :|.| .|.|:.   .:::.|...  |...:||   |:|||
Human    35 SSPGEADTGRRRALMLPAVLQAPGNHQHPHRITNF---FIDNILRPEFGRRKDAGTCCAGAGGGR 96

  Fly    91 GGGGGGGGVASGLSAAAAAAGVAAGLLAA----------AASGANGDRDANGGSGPGSG------ 139
            |||.||.|.|||......|.| :..||.:          .|.||.|...|.|...||.|
Human    97 GGGAGGEGGASGAEGGGGAGG-SEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKT 160

  Fly   140 ---------GGTSGGYAEHKLQL----------------SKSG---------------------- 157
                     ||..||..:..|:.                |::|
Human   161 LSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDR 225

  Fly   158 -------RKPRRR---------RTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKT 206
                   |||:::         |||||..||..|:.:|:..:||:...|..:|:.|:|:|:|:|.
Human   226 PSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKI 290

  Fly   207 WYQNRRTKWKRQN--------QLRLEQLRHQATMEKD 235
            |:||:|.|.|:..        .|..:.|.:.:|..|:
Human   291 WFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKE 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	23/61 (38%)
EN2	NP_001418.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..49		3/13 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..206		30/111 (27%)
		homeobox domain	243..302		24/58 (41%)
		Homeobox	247..300	CDD:306543	23/52 (44%)
		Engrail_1_C_sig	302..331	CDD:313702	4/26 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910