DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11085 and EN1

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:NP_001417.3 Gene:EN1 / 2019 HGNCID:3342 Length:392 Species:Homo sapiens


Alignment Length:227 Identity:65/227 - (28%)
Similarity:92/227 - (40%) Gaps:69/227 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 TRGPGS-----------GTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDRDAN 131
            ||.||:           |...|......|.|...:|..||||||..||...||||:.|.......
Human   161 TRAPGAASLLCAPDANCGPPDGSQPAAAGAGASKAGNPAAAAAAAAAAVAAAAAAAAAKPSDTGG 225

  Fly   132 GGSGPGSG--GGTSGGYAEH--------------------------------------------- 149
            ||||.|:|  |.....|.||                                             
Human   226 GGSGGGAGSPGAQGTKYPEHGNPAILLMGSANGGPVVKTDSQQPLVWPAWVYCTRYSDRPSSGPR 290

  Fly   150 --KLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRR 212
              ||:..|:.::.:|.|||||..||..|:.:|:..:|::...|..:|:.|:|:|:|:|.|:||:|
Human   291 TRKLKKKKNEKEDKRPRTAFTAEQLQRLKAEFQANRYITEQRRQTLAQELSLNESQIKIWFQNKR 355

  Fly   213 TKWKR----QNQLRLEQL-----RHQATMEKD 235
            .|.|:    :|.|.|..:     .|..|..:|
Human   356 AKIKKATGIKNGLALHLMAQGLYNHSTTTVQD 387

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475 22/52 (42%)
EN1NP_001417.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..100
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 132..164 2/2 (100%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 219..251 10/31 (32%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 282..306 3/23 (13%)
Homeobox 306..359 CDD:278475 22/52 (42%)
Engrail_1_C_sig 361..390 CDD:287495 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.