DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11085 and Npm1

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:NP_032748.1 Gene:Npm1 / 18148 MGIID:106184 Length:292 Species:Mus musculus


Alignment Length:38 Identity:11/38 - (28%)
Similarity:17/38 - (44%) Gaps:8/38 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    23 DSELELSNDDSDIDIED--------RSTPDSTAAGCQQ 52
            |.|.:..:||.|.|.|:        :|..|:.|...|:
Mouse   168 DDEDDEDDDDDDFDEEETEEKVPVKKSVRDTPAKNAQK 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475
Npm1NP_032748.1 Required for interaction with SENP3. /evidence=ECO:0000250 1..185 7/16 (44%)
Necessary for interaction with APEX1. /evidence=ECO:0000250 1..117
Nucleoplasmin 18..116 CDD:308605
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 138..248 11/38 (29%)
Nuclear localization signal. /evidence=ECO:0000255 152..157
Nuclear localization signal. /evidence=ECO:0000255 190..196 1/5 (20%)
Required for nucleolar localization. /evidence=ECO:0000250 241..292
NPM1-C 243..291 CDD:318505
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0488
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.