DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Lhx9

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001036042.1	Gene:	Lhx9 / 16876	MGIID:	1316721	Length:	397	Species:	Mus musculus

Alignment Length:	182	Identity:	46/182 - (25%)
Similarity:	67/182 - (36%)	Gaps:	44/182 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 LAAAASGA-----NGDRDANGG-----SGPGSG-------GGTSGGYAEH---KLQLSKSGRKPR 161
            |||.:.|.     ||......|     ..|..|       .|.:...|:|   ..|.....:|.:
Mouse   204 LAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNENEADHLDRDQQPYPPSQKTK 268

  Fly   162 RRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQL 226
            |.||:|.|.||..::..|.........|...:|:...|::..::.|:||.|.|::| |.||
Mouse   269 RMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRR-NLLR---- 328

  Fly   227 RHQATMEKDFVVQDGGG---AGG--LGCCPSGLSSSFSAAAAAAAAA--SNP 271
                        |:.||   |.|  |...||..|.:.:....|....  :||
Mouse   329 ------------QENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNP 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	15/52 (29%)
Lhx9	NP_001036042.1	LIM1_Lhx2	61..124	CDD:188853
		LIM2_Lhx2_Lhx9	129..187	CDD:188763
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	248..272		5/23 (22%)
		Homeobox	271..323	CDD:278475	15/51 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	330..365		9/34 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	378..397
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910