DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Lbx1

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_034821.2	Gene:	Lbx1 / 16814	MGIID:	104867	Length:	282	Species:	Mus musculus

Alignment Length:	212	Identity:	63/212 - (29%)
Similarity:	83/212 - (39%)	Gaps:	70/212 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 AAGLLAAAASGANGDRDANGG-----------------------------------SGPGSGGGT 142
            ||.|||||      |:.|.||                                   :..|..|.|
Mouse    56 AAHLLAAA------DKHAPGGLPLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMT 114

  Fly   143 SGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTW 207
            ..|..:       :.:|.|:.|||||:.|:..||::|..|||||.|||..:|:.|.|:..||.||
Mouse   115 IFGQRQ-------TPKKRRKSRTAFTNHQIYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITW 172

  Fly   208 YQNRRTKWKRQNQLRLEQLRHQ------------------ATMEKDFVVQDGGGAGGLGCCPSGL 254
            :||||.|.||.    ||:::..                  |.:|::.....|||.||.|...|..
Mouse   173 FQNRRAKLKRD----LEEMKADVESAKKLGPSGQMDIVALAELEQNSEASGGGGGGGCGRAKSRP 233

  Fly   255 SSSFSAAAAAAAAASNP 271
            .|......|..|....|
Mouse   234 GSPALPPGAPQAPGGGP 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	29/52 (56%)
Lbx1	NP_034821.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36
		Homeobox	128..182	CDD:395001	29/53 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	210..282		12/41 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900