Protein Alignment CG11085 and NKX2-3

DIOPT Version :9

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 92/327 - (28%)
• Similarity: 121/327 - (37%)
• Gaps: 116/327 - (35%)

  Fly    41 STPDSTAAGCQQELLLSHHHRRF---------THHDESSVESCLSATRGPGSGTGSGGGGGGGGG 96
            |||.|.    :..|.|...|:.|         .||..|:  .|:.|. ..|:....||.......
Human     9 STPFSV----KDILNLEQQHQHFHGAHLQADLEHHFHSA--PCMLAA-AEGTQFSDGGEEDEEDE 66

  Fly    97 GGVASGLSAAAAAAGVAAGLLAAAASGANGDRDANGGSGPGSGGGTSGGYA------------EH 149
            |...|.|::.|||                        .|.|..|....||.            ||
Human    67 GEKLSYLNSLAAA------------------------DGHGDSGLCPQGYVHTVLRDSCSEPKEH 107

  Fly   150 K-------------LQLSKS--------------GRKPRRR---RTAFTHAQLAYLERKFRCQKY 184
            :             .||.||              ..|||.|   |..|:.||:..|||:|:.|:|
Human   108 EEEPEVVRDRSQKSCQLKKSLETAGDCKAAEESERPKPRSRRKPRVLFSQAQVFELERRFKQQRY 172

  Fly   185 LSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQA------TMEKDFVVQDG-- 241
            ||..:|..:|.:|.|:.||||.|:||||.|.|||.|.:..:|...|      .:....:|:||
Human   173 LSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSLELGAHAPPPPPRRVAVPVLVRDGKP 237

  Fly   242 ---------GGAGGLGCCPSGLSS------SFSAAAAAAAAASNPCNFLTSAAAAAIFRNVGYVH 291
                     |....:|......:|      ..||||||||||        :|||||.:.:   .:
Human   238 CVTPSAQAYGAPYSVGASAYSYNSFPAYGYGNSAAAAAAAAA--------AAAAAAAYSS---SY 291

  Fly   292 GC 293
            ||
Human   292 GC 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	27/55 (49%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		4/20 (20%)
		HOX	148..204	CDD:197696	27/55 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910