DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Hlx

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_032276.1	Gene:	Hlx / 15284	MGIID:	96109	Length:	476	Species:	Mus musculus

Alignment Length:	184	Identity:	44/184 - (23%)
Similarity:	68/184 - (36%)	Gaps:	63/184 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 RKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLR 222
            ||....|..|::.|...||::|..|||::..||..:|..|.|::.|||.|:||||.||:...:.:
Mouse   271 RKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQ 335

  Fly   223 LEQLRHQATMEK---------------------------------DFVVQD-------------- 240
            .::.:.:...||                                 |....|
Mouse   336 AQKDKDKEAGEKPSGGVPAEGEREERSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQT 400

  Fly   241 ----GGGAGGL---GCCPSGLSSSFSAAAA---------AAAAASNPCNFLTSA 278
                ...||.|   ....||.|.|||:.::         :|::....|:.|.||
Mouse   401 TVIKASAAGALITASSSTSGSSFSFSSTSSLGSGNTHVGSASSLGGNCSELPSA 454

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	23/52 (44%)
Hlx	NP_032276.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	120..169
		COG5576	224..>341	CDD:227863	26/69 (38%)
		Homeobox	276..329	CDD:278475	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..401		5/72 (7%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	413..476		11/42 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900