DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG11085 and NKX2-6

DIOPT Version :9

Sequence 1:NP_572815.3 Gene:CG11085 / 32213 FlyBaseID:FBgn0030408 Length:295 Species:Drosophila melanogaster
Sequence 2:NP_001129743.2 Gene:NKX2-6 / 137814 HGNCID:32940 Length:301 Species:Homo sapiens


Alignment Length:243 Identity:78/243 - (32%)
Similarity:101/243 - (41%) Gaps:45/243 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 GSGTGSGGGGGGG--------GGGGVASGLSAAAAAAGVAAGLLAAAASGANGDRDANGGSGPGS 138
            ||...:.|||||.        .||...:.|...|...|.....|.||:....|.|....|.| .|
Human    52 GSEVHNAGGGGGDRKLDGSEPPGGPCEAVLEMDAERMGEPQPGLNAASPLGGGTRVPERGVG-NS 115

  Fly   139 GGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQ 203
            |....||.:|     ....|:.|:.|..|:.||:..|||:|:.|:|||..:|..:|..|.|:.||
Human   116 GDSVRGGRSE-----QPKARQRRKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQ 175

  Fly   204 VKTWYQNRRTKWKRQNQLR-LEQLRHQATMEK---DFVVQDGGGAGGLGCCPSGLSSSFSAAAAA 264
            ||.|:||||.|.|||.|.: ||...|..|..:   ..:|:||....|.|.......|.:|||.:.
Human   176 VKIWFQNRRYKCKRQRQDKSLELAGHPLTPRRVAVPVLVRDGKPCLGPGPGAPAFPSPYSAAVSP 240

  Fly   265 --------------------AAAASNPCNFLTSAAAAAIFRNVGYVHG 292
                                |.|.|.|......|:|       |:.||
Human   241 YSCYGGYSGAPYGAGYGTCYAGAPSGPAPHTPLASA-------GFGHG 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11085NP_572815.3 Homeobox 163..216 CDD:278475 26/52 (50%)
NKX2-6NP_001129743.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 22..135 26/88 (30%)
HOX 132..188 CDD:197696 27/55 (49%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.