DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Crx

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_001106801.1	Gene:	Crx / 12951	MGIID:	1194883	Length:	323	Species:	Mus musculus

Alignment Length:	201	Identity:	55/201 - (27%)
Similarity:	75/201 - (37%)	Gaps:	54/201 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 AAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQ 182
            |.|.||.|.|                  .....:..|.:.||.||.||.||.:||..||..|...
Mouse    39 ALALSGPNVD------------------LMHQAVPYSSAPRKQRRERTTFTRSQLEELEALFAKT 85

  Fly   183 KYLSVADRSDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAG-- 245
            :|..|..|.:||..:||.|::|:.|::|||.|.::|.|.:.:|.:......|....:...|..
Mouse    86 QYPDVYAREEVALKINLPESRVQVWFKNRRAKCRQQRQQQKQQQQPPGAQTKARPAKRKAGTSPR 150

  Fly   246 -GLGCC--PSGLSSSFS-----------------------------AAAAAAAAASNPCNFLTSA 278
             ....|  |.|:|.|:|                             .|..|...||.|.  ||||
Mouse   151 PSTDVCTDPLGISDSYSPSLPGPSGSPTTAVATVSIWSPASEAPLPEAQRAGLVASGPS--LTSA 213

  Fly   279 AAAAIF 284
            ..|..:
Mouse   214 PYAMTY 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	23/52 (44%)
Crx	NP_001106801.1	Homeobox	67..117	CDD:278475	22/49 (45%)
Crx	NP_001106801.1	TF_Otx	188..273	CDD:281521	10/34 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910