DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Phox2a

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_032913.1	Gene:	Phox2a / 11859	MGIID:	106633	Length:	280	Species:	Mus musculus

Alignment Length:	235	Identity:	65/235 - (27%)
Similarity:	86/235 - (36%)	Gaps:	55/235 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 SSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAA--ASGANGDRDAN 131
            :|.:||::|......|   ..|.....||...|.|..|..|||.....|.::  |.||..|..
Mouse     7 NSYDSCVAAMEASAYG---DFGACSQPGGFQYSPLRPAFPAAGPPCPALGSSNCALGALRDHQ-- 66

  Fly   132 GGSGPGSGGGTSGGYAEHKLQLSKSG----RKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSD 192
              ..|.|.       ..:|.....||    ||.||.||.||.|||..|||.|....|..:..|.:
Mouse    67 --PAPYSA-------VPYKFFPEPSGLHEKRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREE 122

  Fly   193 VAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAGGLGC-------- 249
            :|..::|:|.:|:.|:||||.|:::|         .:|...|......|...|...|
Mouse   123 LALKIDLTEARVQVWFQNRRAKFRKQ---------ERAASAKGAAGATGAKKGEARCSSEDDDSK 178

  Fly   250 ------------------CPSGLSSSFSAAAAAAAAASNP 271
                              .||..|...|.:...||..|.|
Mouse   179 ESTCSPTPDSTASLPPPPAPSLASPRLSPSPLPAALGSGP 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	23/52 (44%)
Phox2a	NP_032913.1	Homeobox	94..147	CDD:395001	23/52 (44%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..244		14/83 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..280
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910