DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and Alx3

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	NP_031467.1	Gene:	Alx3 / 11694	MGIID:	1277097	Length:	343	Species:	Mus musculus

Alignment Length:	232	Identity:	64/232 - (27%)
Similarity:	96/232 - (41%)	Gaps:	29/232 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 GGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDRD--ANGGSGPGS-----GGGTSGGY 146
            |.|....||....|.:.|...|..||...........|.||  :|..:.||.     ....|.|.
Mouse    76 GPGPVLNGGHFYEGSAEAEEKASKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGL 140

  Fly   147 AEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQNR 211
            .: .::|:|:..|.||.||.|:..||..||:.|:...|..|..|..:|...:|:|.:|:.|:|||
Mouse   141 PD-SMELAKTKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNR 204

  Fly   212 RTKW-KRQNQLRLEQLRHQATMEKDFVV----------------QDGGGAGGLGC--CPSGLSSS 257
            |.|| ||:...::::.|:..|...|..|                ..|.|:.|..|  .|.|:.|
Mouse   205 RAKWRKRERYGKMQEGRNPFTTAYDISVLPRTDSHPQLQNSLWPSPGSGSPGGPCLMSPEGIPS- 268

  Fly   258 FSAAAAAAAAASNPCNFLTSAAAAAIFRNVGYVHGCP 294
             ...:..:.:..|...|:...|:.|....:..:||.|
Mouse   269 -PCMSPYSHSHGNVAGFMGVPASPAAHPGIYSIHGFP 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	22/53 (42%)
Alx3	NP_031467.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..122		13/45 (29%)
		SP2	32..>141	CDD:281067	17/64 (27%)
		Homeobox	157..209	CDD:278475	21/51 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	309..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910