Protein Alignment CG11085 and CDX2

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: XP_011533177.1
• Gene: CDX2 / 1045
• HGNCID: 1806
• Length: 321
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 58/215 - (26%)
• Similarity: 86/215 - (40%)
• Gaps: 66/215 - (30%)

  Fly    75 LSATRGPGSG-------------TGSGGGGGGGGGGGVASGLS--AAAAAAGVAAGL-------- 116
            |.:.:.||..             .|...||.......||.||:  :.|||.|.::..
Human    55 LDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHP 119

  Fly   117 ------LAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSG---------RKPRRR--- 163
                  .|||.|.|:|....   ..||..|..:...||   |||..|         |||.::
Human   120 HHHPHHPAAAPSCASGLLQT---LNPGPPGPAATAAAE---QLSPGGQRRNLCEWMRKPAQQSLG 178

  Fly   164 -------------------RTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQ 209
                               |..:|..|...||::|...:|:::..::::|.||.|||.|||.|:|
Human   179 SQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQ 243

  Fly   210 NRRTKWKRQNQLRLEQLRHQ 229
            |||.|.::.|:.:|:|.:.|
Human   244 NRRAKERKINKKKLQQQQQQ 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	22/77 (29%)
CDX2	XP_011533177.1	Caudal_act	13..179	CDD:461413	32/129 (25%)
		Homeodomain	196..251	CDD:459649	22/54 (41%)