DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and CDX2

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_011533177.1	Gene:	CDX2 / 1045	HGNCID:	1806	Length:	321	Species:	Homo sapiens

Alignment Length:	215	Identity:	58/215 - (26%)
Similarity:	86/215 - (40%)	Gaps:	66/215 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 LSATRGPGSG-------------TGSGGGGGGGGGGGVASGLS--AAAAAAGVAAGL-------- 116
            |.:.:.||..             .|...||.......||.||:  :.|||.|.::..
Human    55 LDSAQSPGPSWPAAYGAPLREDWNGYAPGGAAAAANAVAHGLNGGSPAAAMGYSSPADYHPHHHP 119

  Fly   117 ------LAAAASGANGDRDANGGSGPGSGGGTSGGYAEHKLQLSKSG---------RKPRRR--- 163
                  .|||.|.|:|....   ..||..|..:...||   |||..|         |||.::
Human   120 HHHPHHPAAAPSCASGLLQT---LNPGPPGPAATAAAE---QLSPGGQRRNLCEWMRKPAQQSLG 178

  Fly   164 -------------------RTAFTHAQLAYLERKFRCQKYLSVADRSDVAETLNLSETQVKTWYQ 209
                               |..:|..|...||::|...:|:::..::::|.||.|||.|||.|:|
Human   179 SQALTSPSSTVKTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQ 243

  Fly   210 NRRTKWKRQNQLRLEQLRHQ 229
            |||.|.::.|:.:|:|.:.|
Human   244 NRRAKERKINKKKLQQQQQQ 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	22/74 (30%)
CDX2	XP_011533177.1	Caudal_act	13..171	CDD:282574	29/121 (24%)
CDX2	XP_011533177.1	Homeobox	198..250	CDD:278475	22/51 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910