DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11085 and arx

DIOPT Version :9

Sequence 1:	NP_572815.3	Gene:	CG11085 / 32213	FlyBaseID:	FBgn0030408	Length:	295	Species:	Drosophila melanogaster
Sequence 2:	XP_002933659.1	Gene:	arx / 100486727	XenbaseID:	XB-GENE-483940	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	330	Identity:	80/330 - (24%)
Similarity:	120/330 - (36%)	Gaps:	109/330 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 IRDLLGDLINRRQTDSELELSNDDSDIDIEDRSTPDSTAAGCQQELLLSHH----------HRRF 63
            ::|.||.|       |:.....||.|.:.||....:..    :.|....|:          |.:.
Frog   183 LQDRLGAL-------SQSPRDEDDDDEEDEDEEEEEEE----EDEANKQHNPNNSSNPNRAHLQE 236

  Fly    64 THHDESSVESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGDR 128
            ..|.:...:........||.||.                     |.......|:..::
Frog   237 QQHPQFQSQQSQQQQPPPGCGTD---------------------AELSPKEELMLHSS------- 273

  Fly   129 DANGGSGPGSGGGTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADRSDV 193
            ||:|..|..|...::|..:|..:    ..||.||.||.||..||..|||.|:...|..|..|.::
Frog   274 DADGKDGEDSVCLSAGSDSEEGM----LKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREEL 334

  Fly   194 AETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKDFVVQDGGGAGGL-------GCCP 251
            |..|:|:|.:|:.|:||||.||::         |.:|..:..        |.||       ...|
Frog   335 AMRLDLTEARVQVWFQNRRAKWRK---------REKAGAQTH--------APGLPFPGPLSASHP 382

  Fly   252 SG--------------LSSSFSAAAAAAAAA-----------------SNPCNFLTSAAAAAIFR 285
            .|              |.|:::|||||||||                 .:|.. |::...||:||
Frog   383 LGPYLDASPFPPHHPALDSAWTAAAAAAAAAFPSLPPPPHGSAALPPSGSPLG-LSTFLGAAVFR 446

  Fly   286 NVGYV 290
            :..::
Frog   447 HPAFI 451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeobox	163..216	CDD:278475	24/52 (46%)
arx	XP_002933659.1	Homeobox	305..358	CDD:365835	25/52 (48%)
arx	XP_002933659.1	OAR	500..518	CDD:367680
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910