Protein Alignment CG11085 and nkx2-1

DIOPT Version :10

• Sequence 1: NP_572815.3
• Gene: CG11085 / 32213
• FlyBaseID: FBgn0030408
• Length: 295
• Species: Drosophila melanogaster
• Sequence 2: XP_002935383.1
• Gene: nkx2-1 / 100135015
• XenbaseID: XB-GENE-485985
• Length: 346
• Species: Xenopus tropicalis
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 111/292 - (38%)
• Gaps: 45/292 - (15%)

  Fly     7 FLIRDLLGDLINRRQTDSELELSNDDSDIDIEDRSTPDSTAAGCQQELLLSHHHRRFTHHDESSV 71
            |.:.|:|          |.||.|.....::......|.|.|....|....|.......|:...|.
 Frog    11 FSVSDIL----------SPLEESYKKVAMESAGLGAPLSAAYRQSQVSQASMQQHGMGHNGPVSA 65

  Fly    72 ESCLSATRGPGSGTGSGGGGGGGGGGGVASGLSAAAAAAGVAAGLLAAAASGANGD-------RD 129
            ...::|...|.....:.||...|..|.:.: :|.............|....|||.|       |.
 Frog    66 AYHMTAAGVPQLSHTTMGGYCNGNLGNLGN-MSELPPYQDTMRNSSATGWYGANPDPRFSTISRF 129

  Fly   130 ANGGSGPGSGG----GTSGGYAEHKLQLSKSGRKPRRRRTAFTHAQLAYLERKFRCQKYLSVADR 190
            ....||...||    |:.|...:....|..:.|  |:||..|:.||:..|||:|:.|||||..:|
 Frog   130 MGPSSGMNMGGLGNMGSLGDVGKSMTPLQATPR--RKRRVLFSQAQVYELERRFKQQKYLSAPER 192

  Fly   191 SDVAETLNLSETQVKTWYQNRRTKWKRQNQLRLEQLRHQATMEKD----------------FVVQ 239
            ..:|..::|:.||||.|:||.|.|.|||.:.:..|.:    |::|                .:|:
 Frog   193 EHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQ----MQQDNSSCQQQQSPRRVAVPVLVK 253

  Fly   240 DGGGA-GGLGCCPSGLSSSFSAAAAAAAAASN 270
            ||... .|.....:.|.|.....|.|....||
 Frog   254 DGKPCQAGSNTPTAALQSHQQQTATAITVTSN 285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11085	NP_572815.3	Homeodomain	161..217	CDD:459649	27/55 (49%)
nkx2-1	XP_002935383.1	Homeodomain	163..219	CDD:459649	27/55 (49%)